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Related Concept Videos

Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
Acute Pancreatitis I: Introduction01:25

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

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Related Experiment Video

Updated: May 17, 2026

A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice
14:39

A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice

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[Glycemic dysfunction prevalence post acute pancreatitis. A prospective study].

María Jimena Soutelo1, Melina Saban, María Clara Fritz

  • 1Servicio de Endocrinología, Complejo Médico (PFA) Churruca Visca, Uspallata 3400 CP: C1437JCP Ciudad Autónoma de Buenos Aires, Argentina. jimesoutelo@arnet.com.ar

Revista De Gastroenterologia Del Peru : Organo Oficial De La Sociedad De Gastroenterologia Del Peru
|November 7, 2012
PubMed
Summary
This summary is machine-generated.

Mild acute pancreatitis is linked to carbohydrate metabolism issues, with over 65% of patients showing signs of pre-diabetes or diabetes. Older patients and those with metabolic syndrome were more affected.

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Last Updated: May 17, 2026

A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice
14:39

A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice

Published on: January 9, 2026

Isolation of Human Islets from Partially Pancreatectomized Patients
11:10

Isolation of Human Islets from Partially Pancreatectomized Patients

Published on: July 30, 2011

Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
07:38

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Area of Science:

  • Endocrinology
  • Gastroenterology
  • Metabolic Disorders

Context:

  • Mild acute pancreatitis (MAP) affects a significant patient population.
  • Carbohydrate metabolism dysfunction is a known comorbidity in various conditions.
  • Early identification of metabolic alterations is crucial for patient management.

Purpose:

  • To determine the prevalence of impaired carbohydrate metabolism in patients with MAP.
  • To identify risk factors associated with glucose metabolism abnormalities in MAP patients.

Summary:

  • Eighty-five patients with MAP underwent routine laboratory tests and Oral Glucose Tolerance Tests (OGTT).
  • Exclusion criteria included pre-existing diabetes, alcoholic pancreatitis, severe hypertriglyceridemia, and recurrent/severe pancreatitis.
  • Results indicated that 65.66% of patients exhibited impaired glucose metabolism (pre-diabetes or diabetes), with higher prevalence in older patients and those with metabolic syndrome.

Impact:

  • Highlights a significant link between MAP and glucose metabolism dysfunction.
  • Suggests routine screening for carbohydrate metabolism issues in MAP patients.
  • Provides data for improved risk stratification and management strategies for MAP patients.