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Published on: January 9, 2026
[Glycemic dysfunction prevalence post acute pancreatitis. A prospective study]
María Jimena Soutelo1, Melina Saban, María Clara Fritz
1Servicio de Endocrinología, Complejo Médico (PFA) Churruca Visca, Uspallata 3400 CP: C1437JCP Ciudad Autónoma de Buenos Aires, Argentina. jimesoutelo@arnet.com.ar
Objective:
To estimate the prevalence of altered metabolism of carbohydrates in patients with mild acute pancreatitis.
Methods:
We included 85 patients diagnosed with pancreatitis. We used to evaluate prognosis Balthazar and Ranson criteria. All patients were interviewed and examined. Was performed routine laboratory and Oral glucose tolerance test (OGTT) We excluded patients with previous diagnosis of diabetes mellitus, alcoholic pancreatitis, severe hypertriglyceridemia and recurrent/ severe pancreatitis.
Results:
30 women and 27 men. After performing the OGTT were classified into three groups. Group 1 (n: 19): normal OGTT; Group 2 (n: 33): GAA, IHC, or both, and Group 3 (n = 5): with diabetes mellitus. Patients in group 3 had a higher average age (p = 0.02), and higher diastolic blood pressure (DBP) (p = 0.048). We observe a significant difference in fasting glucose values (p = 0.0001) and 120 minutes post-OGTT in all groups (p = 0.0001). HOMA was found higher (p = 0.031) in group 2.
Conclusions:
This study showing a link between mild acute pancreatitis and dysfunction of glucose metabolism, which found older patients, DBP and those with metabolic syndrome, had a higher prevalence of 65.66% of Pre diabetes and diabetes.
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Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
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