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Updated: May 17, 2026

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
Intraoperative continuous hemodiafiltration with selective venous drainage of ischemic limbs
Nobuo Kondo1, Seiichiro Wariishi, Hideaki Nishimori
1Department of Surgery II, Kochi Medical School, Kohasu, Oko-cho, Nankoku, Kochi, 783-8505, Japan. jm-kondo-nobuo@kochi-u.ac.jp
Abstract:
We report two cases of acute limb ischemia with threatened myonephropathic metabolic syndrome (MNMS) in which continuous hemodiafiltration (CHDF) was started before revascularization with selective drainage from the clamped femoral vein of ischemic limb and return of processed blood into the contralateral femoral vein. It was aimed to optimise the removal of metabolites which were produced by myolysis following reperfusion as well as to minimize the deviation of metabolites into the systemic circulation. Both cases had uneventful postoperative course without MNMS and the limbs were salvaged.
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