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Updated: May 17, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Orbital chondrosarcoma arising from paranasal sinuses.

Hayyam Kiratli¹, Ozlem Dikmetaş, Berçin Tarlan

¹Ocular Oncology Service, Department of Ophthalmology, Hacettepe University School of Medicine, Sıhhiye, Ankara, Turkey. hkiratli@hacettepe.edu.tr

International Ophthalmology

|November 7, 2012

Summary

This study details multidisciplinary treatment for rare sino-orbital chondrosarcomas. Endoscopic surgery offers lower morbidity, but careful margin control is vital to prevent recurrence.

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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

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Published on: January 17, 2018

Area of Science:

Oncology
Otorhinolaryngology
Neurosurgery

Background:

Chondrosarcoma, a rare bone tumor, can extend into the orbit from paranasal sinuses.
Sino-orbital chondrosarcomas present unique challenges due to their location and potential for extensive invasion.

Observation:

Three patients with extensive sino-orbital chondrosarcomas (maxillary, sphenoidal, ethmoidal origins) underwent multidisciplinary treatment.
Magnetic resonance imaging revealed characteristic signal intensities for these tumors.
Intranasal endoscopic surgery, often combined with other approaches, was the primary treatment modality.

Findings:

Two patients experienced recurrences, necessitating wider surgical excision.
Fractionated stereotactic radiotherapy was employed in two cases.
Tumor grades varied (I and III), with no regional spread or distant metastasis observed.
All patients achieved disease-free status at 2-4 years post-treatment.

Implications:

Endoscopic surgery demonstrates reduced morbidity for sino-orbital chondrosarcomas involving posterior orbit.
Incomplete surgical margin control can lead to recurrences, underscoring the need for potentially more radical surgical strategies.
Multidisciplinary management is crucial for optimizing outcomes in these complex cases.