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Related Concept Videos

Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Radical Chain-Growth Polymerization: Mechanism01:09

Radical Chain-Growth Polymerization: Mechanism

The radical chain-growth polymerization mechanism consists of three steps: initiation, propagation, and termination of polymerization. The polymerization initiates when a free radical generated from the radical initiator adds to the unsaturated bond in the monomer. The unpaired electron of the free radical and one π electron in the unsaturated bond creates a σ bond between the free radical and the monomer. As a result, the other π electron in the unsaturated bond converts this species into the...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Whole Body Regeneration01:33

Whole Body Regeneration

Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential; even...
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DNA replication is carried out by a large complex of proteins that act in a coordinated matter to achieve high-fidelity DNA replication. Together this complex is known as the DNA replication machinery or the replisome.
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Rapid Verification of Terminators Using the pGR-Blue Plasmid and Golden Gate Assembly
09:51

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Published on: April 25, 2016

Parthenium the terminator: An update.

Chembolli Lakshmi1, Cr Srinivas

  • 1Department of Dermatology, PSG Hospitals and PSGIMSR, Coimbatore - 641 004, Tamil Nadu, India.

Indian Dermatology Online Journal
|November 7, 2012
PubMed
Summary
This summary is machine-generated.

Parthenium dermatitis, a skin condition caused by the Parthenium hysterophorus weed, presents unique challenges. This article explores its uncommon symptoms, pathogenesis, and updated management strategies for this widespread allergic contact dermatitis.

Keywords:
Atopic dermatitisparthenium dermatitispatch and prick testtype I hypersensitivitytype IV hypersensitivity

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Area of Science:

  • Dermatology
  • Allergology
  • Environmental Health

Background:

  • Parthenium dermatitis is an allergic contact dermatitis triggered by airborne allergens from the Parthenium hysterophorus weed.
  • This condition, often referred to as a "scourge," causes significant patient distress.
  • The Compositae family weed is a common environmental allergen in many regions.

Purpose of the Study:

  • To discuss uncommon clinical presentations of Parthenium dermatitis.
  • To provide newer insights into the pathogenesis of this allergic skin condition.
  • To review current and emerging management strategies for Parthenium dermatitis.

Main Methods:

  • Literature review of Parthenium dermatitis cases and research.
  • Analysis of recent studies on allergic contact dermatitis mechanisms.
  • Synthesis of clinical guidelines and expert opinions on Parthenium dermatitis management.

Main Results:

  • Parthenium dermatitis can manifest in atypical ways beyond typical eczema.
  • Advances in understanding immune responses to Parthenium allergens are highlighted.
  • Effective management involves allergen avoidance, topical therapies, and potentially systemic treatments.

Conclusions:

  • Parthenium dermatitis requires recognition of its diverse presentations.
  • Further research into pathogenesis may reveal novel therapeutic targets.
  • Integrated management approaches are crucial for controlling this distressing condition.