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Left ventricular function after permanent pacemaker in pacemaker clinic follow-up
Jarin Assavahanrit1, Peerapat Katekangplu, Pornwalee Porapakkham
1Central Chest Institute of Thailand, Nonthaburi, Thailand. cardiocc02@gmail.com
Insights
Left ventricular dysfunction is common in patients with chronic right ventricular pacing. Hypertension, coronary artery disease, and increased pacing percentage are associated with this condition.
Area of Science:
- Cardiology
- Cardiac Electrophysiology
- Echocardiography
Background:
- Chronic right ventricular pacing can negatively impact left ventricular (LV) function, potentially leading to asymptomatic dysfunction.
- The prevalence of LV dysfunction (LVEF < 50%) in Thai patients undergoing RV pacing is unknown.
Purpose of the Study:
- To determine the prevalence of LV dysfunction in Thai patients with chronic RV pacing.
- To identify clinical and pacing parameters associated with LV dysfunction in this population.
Main Methods:
- Retrospective review of 118 patients from the Central Chest Institute of Thailand pacemaker clinic.
- Analysis of demographic, pacemaker, and echocardiographic data for LV function in patients with over one year of implantation.
Main Results:
- Left ventricular systolic dysfunction was identified in 17.80% (21/118) of patients.
- Patients with LV dysfunction exhibited larger LV size and thinner LV walls compared to those without.
- Correlations were found with hypertension, coronary artery disease, moderate to severe mitral regurgitation, and moderate to severe tricuspid regurgitation.
Conclusions:
- Left ventricular dysfunction is a significant concern following pacemaker implantation.
- Factors associated with LV dysfunction include prior LV issues, hypertension, coronary artery disease, and a higher percentage of ventricular pacing.
- Pacing mode and lead site did not show a correlation with LV dysfunction.
Background:
Chronic right ventricular pacing has deleterious effects to left ventricular function which may be asymptomatic. Prevalence of LV dysfunction (LVEF < 50%) in RV pacing in Thai patients is not known.
Material And Method:
Patients in the Central Chest Institute of Thailand (CCIT) pacemaker clinic were retrospectively reviewed for their demographic and pacemaker data together with echocardiographic data for LV function. Analysis was done for those who were implanted for more than one year period.
Results:
Among the studied 118patients, male = 51 and female = 67, mean follow-up time 6.43 +/- 5.66 years, LV systolic dysfunction was identified in 21 (17.80%). Compared to those with no LV dysfunction, echocardiographic parameters showed larger LVsize (EDD 49.86 +/- 8.95 vs. 43.81 +/- 5.56 mm) and less thickness of the LV wall (11.05 +/- 1.60 vs. 12.49 +/- 2.79 mm). Studied clinical and pace parameters for correlation were hypertension (p = 0.048), coronary artery disease (p = 0.008), percent of ventricular pacing (p = 0.06), duration after implantation (p = 0.23), mode of pacing (p = 0.275), indication of implantation (p = 0.32, site of pacing lead (p = 0.279), moderate to severe MR (p = 0.003) and moderate to severe TR (p = 0.04).
Conclusion:
LV dysfunction after pacemaker implantation was not infrequent. Parameters correlated to it were previous LV dysfunction, hypertension, coronary artery disease and increased amount of ventricular pacing. Mode of pacing and site of pacing lead were not correlated.
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