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Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
Published on: March 7, 2025
Rheumatological manifestations occurring in patients with diabetes mellitus
1Department of Internal Medicine, Hospital de San Juan, Alicante, Spain. sara23x@hotmail.com
Objectives:
In this review we focus on the evidence for an association between musculoskeletal (MSK) manifestations and diabetes mellitus (DM).
Method:
A systematic literature review was performed using the PubMed database for articles that have been published in the past 8 years (from January 2003 to August 2011) for keywords referring to MSK manifestations and DM. Where possible we have distinguished between manifestations that occur in type 1 as opposed to type 2 DM. However, this was not easy because many reports do not make the distinction.
Results:
MSK manifestations of DM are relatively common. The duration of DM is often linked to the onset of some MSK features.
Conclusions:
Patients with DM have been reported to have an increased prevalence of several MSK manifestations. It is important to be aware of MSK complications of DM. A better control of the glucose level may be useful.
Insights
Musculoskeletal (MSK) issues are common in diabetes mellitus (DM). Managing blood glucose levels may help reduce the risk of these common MSK complications in patients with DM.
Area of Science:
- Endocrinology
- Rheumatology
- Internal Medicine
Background:
- Diabetes mellitus (DM) is a complex metabolic disorder with various systemic complications.
- Musculoskeletal (MSK) manifestations are increasingly recognized as a significant comorbidity in patients with DM.
Purpose of the Study:
- To review the existing evidence on the association between musculoskeletal manifestations and diabetes mellitus.
- To highlight the prevalence and nature of MSK complications in diabetic patients.
Main Methods:
- A systematic literature review was conducted using PubMed.
- Searched for articles published between January 2003 and August 2011.
- Keywords included 'musculoskeletal manifestations' and 'diabetes mellitus'.
Main Results:
- Musculoskeletal manifestations are relatively common in individuals with diabetes mellitus.
- The duration of diabetes mellitus often correlates with the development of certain MSK features.
- Distinguishing between Type 1 and Type 2 DM for MSK manifestations was challenging due to reporting inconsistencies.
Conclusions:
- Patients with diabetes mellitus exhibit an increased prevalence of several MSK manifestations.
- Awareness of these MSK complications is crucial for effective patient management.
- Improved glycemic control may play a role in mitigating MSK complications associated with diabetes.
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