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Updated: May 17, 2026
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A Simplified Technique for Producing an Ischemic Wound Model
Published on: May 2, 2012
Wound healing: the evidence for hyperbaric oxygen therapy
1Florence Nightingale School of Nursing & Midwifery, Kings College London.
British Journal of Nursing (Mark Allen Publishing)
|November 8, 2012
Summary
Hyperbaric oxygen therapy (HBOT) aids chronic wound healing by increasing oxygen levels. While effective for diabetic foot ulcers, long-term benefits require further investigation.
Area of Science:
- Wound Healing Research
- Hyperbaric Medicine
- Oxygen Therapy
Background:
- Hyperbaric oxygen therapy (HBOT) has been explored for wound healing for over 40 years.
- HBOT involves administering 100% oxygen in a multi-place compression chamber.
- Oxygen is crucial for normal wound healing processes.
Purpose of the Study:
- To review the evidence supporting hyperbaric oxygen therapy (HBOT) as an adjuvant wound healing treatment.
- To assess the efficacy of HBOT in chronic wounds unresponsive to conventional therapies.
Main Methods:
- Review of animal studies and clinical trials on HBOT for wound healing.
- Analysis of HBOT's physiological effects on oxygen transport and wound environments.
Main Results:
- HBOT demonstrates benefits for the hypovascular-hypocellular-hypoxic environment of chronic wounds.
- Evidence supports HBOT's effectiveness in healing diabetic foot ulcers.
- Long-term benefits of HBOT for diabetic foot ulcers are not consistently evident.
Conclusions:
- HBOT is an adjunctive therapy that enhances wound healing when conventional treatments are insufficient.
- The application of HBOT should complement, not replace, approved wound care practices.
- Further research is needed to clarify the long-term efficacy of HBOT for specific wound types.
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