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Updated: May 17, 2026

Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
Unilateral posterior stromal keratitis possibly secondary to Lyme disease
Gregory W Oldham1, Gerami D Seitzman
1Krieger Eye Institute, Sinai Hospital of Baltimore, Baltimore, MD 21215, USA. gwoldham@gmail.com
Purpose:
To report a case of Lyme disease presenting as unilateral posterior stromal keratitis in a pediatric patient.
Methods:
Case report and review of available literature.
Results:
A 13-year-old adolescent with unilateral painless blurry vision presented with prominent posterior corneal stromal haze. A positive Borrelia burgdorferi antibody enzyme immunoassay and Western blot analysis (9 of 10 reactive immunoglobulin G bands and 1 of 3 immunoglobulin M bands) confirmed the diagnosis. Treatment with oral antibiotics and topical corticosteroids were necessary for resolution.
Conclusions:
Lyme disease may present as a unilateral posterior stromal keratitis, even in a pediatric population. Treatment requires both systemic and topical therapy.

