Related Experiment Video
Updated: May 17, 2026

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children
Published on: April 29, 2013
Internalizing symptoms and functional disability in children with noncardiac chest pain and innocent heart murmurs
Jennifer L Lee1, Jordan Gilleland, Robert M Campbell
1Department of Psychology, University of Georgia, Athens, GA 30602-3013, USA. jenlee09@gmail.com
Insights
Children with noncardiac chest pain (NCCP) experience more anxiety, depression, and functional disability than those with innocent heart murmurs (IHMs). Psychosocial factors significantly impact NCCP in pediatric patients.
Area of Science:
- Pediatric Cardiology
- Child Psychology
- Psychosomatic Medicine
Background:
- Noncardiac chest pain (NCCP) is a common pediatric concern.
- Differentiating physical from psychological origins of chest pain is crucial for effective management.
Purpose of the Study:
- To compare internalizing symptoms and functional disability in children with NCCP versus those with innocent heart murmurs (IHMs).
- To investigate the role of psychosocial distress in pediatric noncardiac chest pain.
Main Methods:
- A comparative study involving 67 children with NCCP and 62 children with IHMs.
- Utilized validated measures of psychological functioning and functional disability administered during initial cardiology consultations.
Main Results:
- Children with NCCP reported significantly higher levels of anxiety, depression, and anxiety sensitivity compared to children with IHMs.
- Both children with NCCP and their parents reported increased functional disability and somatization.
Conclusions:
- Pediatric patients with NCCP exhibit greater psychosocial distress and functional impairment than healthy children with IHMs.
- Psychosocial factors are integral to the assessment and treatment of noncardiac chest pain in children.
Objective:
To examine the occurrence of internalizing symptoms and functional disability in children with noncardiac chest pain (NCCP) compared with children with innocent heart murmurs (IHMs).
Method:
67 children with NCCP (M [SD] age = 12.61 [2.63]; 68.7% Caucasian) and 62 children with IHM (M [SD] age = 12.67 [2.62]; 50% Caucasian) were recruited from pediatric cardiology offices. Children and parents completed measures of psychological functioning and functional disability during a first visit to the cardiologist before diagnosis.
Results:
Children with NCCP reported greater levels of anxiety, depression, and anxiety sensitivity than children with IHM. Children with NCCP and their parents reported greater levels of functional disability and somatization than children with IHM and their parents.
Conclusion:
Children with NCCP experience greater levels of psychosocial distress and impairment than similarly physically healthy children with IHM. Consideration of psychosocial influences on NCCP would likely be beneficial in aiding assessment and treatment.
Related Concept Videos
Angina III: Clinical Manifestations and Assessment
Mitral Stenosis II: Clinical features and Diagnostic Tests
Heart Sounds
Auscultation is the process of listening to these internal body sounds using a stethoscope. The heart produces four types of sounds, but only two—S1 and S2—can usually be heard with a stethoscope.
S1, also known as the "lub" sound, is caused by the closure of atrioventricular (A-V) valves at the...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Cardiomyopathy III: Hypertrophic Cardiomyopathy
