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Necrotizing fascitis: an epidemiologic study of 102 cases
Mohammad Sadegh Fazeli1, Mohammad Reza Keramati
1Department of Surgery, Imam Hospital, No. 60, Gharib St., Keshavarz Blvd., Tehran, PO Box: 13145-158, Iran.
The Indian Journal of Surgery
|November 8, 2012
Summary
Necrotizing fasciitis, a severe infection, is more common in males and often linked to diabetes. Early surgical intervention is crucial for reducing mortality from this condition.
Area of Science:
- Infectious Diseases
- Surgical Pathology
Background:
- Necrotizing fasciitis is a severe, rapidly progressing infection of deep fascia.
- It can lead to tissue necrosis, shock, organ failure, and death.
Purpose of the Study:
- To evaluate the prevalence of predisposing factors, clinical and paraclinical findings, tissue involvement, and mortality rates of necrotizing fasciitis.
- To analyze data from 102 patients diagnosed between 1995 and 2005.
Main Methods:
- Retrospective analysis of patient data.
- Evaluation of demographic, clinical, microbiological, and outcome variables.
Main Results:
- Higher prevalence in males (2.6:1 ratio).
- Diabetes mellitus was the most common predisposing factor.
- Genital region was the most frequent site of infection; muscles involved in 25.5% of cases.
- Enterococcus faecalis was the most common pathogen; mortality rate was 10.8%.
Conclusions:
- Necrotizing fasciitis has a high mortality rate and often presents with non-specific symptoms.
- Prompt diagnosis and surgical debridement are essential for improving patient outcomes and reducing mortality.
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