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Updated: May 17, 2026

Bovine Mammary Gland Biopsy Techniques
Published on: December 23, 2018
Granulomatous mastitis - a diagnostic dilemma.
Dajiram G Mote1, Raghavendra P Gungi, V Satyanarayana
1Departments of General surgery and pathology, Kamineni Institute of Medical Sciences, Narketpally, Nalgonda, A. P., India.
Granulomatous lobular mastitis (GLM) is a rare benign breast condition that can mimic cancer. Early diagnosis and treatment, like surgery and steroids, are key to managing this pregnancy-associated disease.
Area of Science:
- Pathology
- Oncology
- Radiology
Background:
- Granulomatous lobular mastitis (GLM) is a rare, benign breast disease.
- Characterized by chronic, non-caseating granulomatous lobulitis, it can be misdiagnosed as breast cancer.
- GLM often occurs postpartum and may necessitate mastectomy if misdiagnosed.
Purpose of the Study:
- To report a case of GLM treated with local excision and steroid therapy.
- To increase awareness of GLM among surgeons and pathologists.
- To highlight diagnostic criteria for GLM.
Main Methods:
- Histopathological examination revealing granulomatous inflammation centered on lobules.
- Clinical presentation and patient history, noting association with pregnancy.
- Treatment involving local excision and postoperative steroid administration.
Main Results:
- The reported case demonstrated characteristic features of GLM.
- Successful management achieved through surgical excision and steroid therapy.
- Increased awareness among clinicians regarding this rare condition.
Conclusions:
- GLM requires accurate diagnosis to avoid unnecessary mastectomy.
- Multidisciplinary approach involving surgeons and pathologists is crucial.
- Steroid therapy can be effective in managing GLM post-excision.
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