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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Related Experiment Video

Updated: May 17, 2026

Murine Model of CD40-activation of B cells
12:24

Murine Model of CD40-activation of B cells

Published on: March 5, 2010

Primary cutaneous CD 30+ anaplastic large cell lymphoma.

S Devaji Rao1, R Ravi, Meera Govindarajan

  • 1Dhanwanthri Surgical Clinic and St. Isabel's Hospital, Chennai, India.

The Indian Journal of Surgery
|November 8, 2012
PubMed
Summary

Cutaneous T cell lymphoma (CTCL) can present as a non-healing ulcer. This specific CTCL type required a multimodality treatment approach for successful healing.

Keywords:
Anaplastic large cell lymphomaNon- Hodgkin’s lymphoma

Related Experiment Videos

Last Updated: May 17, 2026

Murine Model of CD40-activation of B cells
12:24

Murine Model of CD40-activation of B cells

Published on: March 5, 2010

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Cutaneous T cell lymphoma (CTCL) is a diverse group of malignant skin conditions.
  • Accurate diagnosis relies on histological and immunohistochemical analysis.
  • Variable clinical presentations can complicate diagnosis.

Purpose of the Study:

  • To present a case of primary cutaneous CD30+ anaplastic large cell lymphoma.
  • To highlight its presentation as a non-healing ulcer.
  • To discuss the treatment strategy for this specific CTCL variant.

Main Methods:

  • Histopathological examination of skin biopsy.
  • Immunohistochemical staining for CD30 and other markers.
  • Clinical assessment and documentation of treatment response.

Main Results:

  • The patient was diagnosed with primary cutaneous CD30+ anaplastic large cell lymphoma.
  • The condition presented as a persistent, non-healing ulcer.
  • A multimodality treatment approach was implemented.

Conclusions:

  • Primary cutaneous CD30+ anaplastic large cell lymphoma can manifest as a non-healing ulcer.
  • Effective management necessitates a comprehensive, multimodality therapeutic strategy.
  • Early and precise diagnosis is crucial for optimal patient outcomes.