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Patch clamp: a powerful technique for studying the mechanism of acupuncture

D Zhang1

  • 1Department of Mechanics and Engineering Science, Fudan University, Shanghai 200433, China ; Shanghai Research Center for Acupuncture and Meridians, Shanghai 201203, China.

Evidence-Based Complementary and Alternative Medicine : Ecam
|November 8, 2012
PubMed

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Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...