Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Flow01:29

Blood Flow

75.4K
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
75.4K
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

288
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
288
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

221
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
221
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

3.8K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
3.8K
Autoregulation of Blood Flow01:17

Autoregulation of Blood Flow

7.4K
Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....
7.4K
Vascular Resistance01:20

Vascular Resistance

9.9K
Vascular resistance is a critical concept in understanding blood flow dynamics in the circulatory system. It refers to the resistance that blood encounters as it flows through the blood vessels. This resistance is a key factor in determining blood pressure and cardiac workload.
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
9.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk of Falls and Acute Mountain Sickness Symptoms Among Japanese and Foreign Climbers on Mount Fuji.

Wilderness & environmental medicine·2026
Same author

Differential macro- and microvascular function responses to acute mental stress in healthy young men.

Microvascular research·2026
Same author

Hypoxemia and hypercapnia synergistically mediate peripheral vasoconstriction, whereas hypercapnia mediates cerebral vasodilation in resting humans.

American journal of physiology. Regulatory, integrative and comparative physiology·2026
Same author

Gait-Specific Pulmonary Oxygen Uptake Kinetics During Gait Transitions Reflect the Energetics of Walking and Running in Humans.

Medicine and science in sports and exercise·2026
Same author

Differences in Influencing Factors for Fall Risks During Descent on Mount Fuji: A Comparison of the Fujinomiya and Yoshida Routes.

Wilderness & environmental medicine·2025
Same author

Japanese steam sand bath heat therapy mediates comparable reductions in blood pressure with smaller discomfort and respiratory strains than hot water immersion and sauna.

European journal of applied physiology·2025
Same journal

A Systematic Review of the Effectiveness of Assessing Skin Changes for Chronic Venous Insufficiency in People With Dark Skin Tones and the Impact on the Patient Journey and Clinical Care.

International journal of vascular medicine·2026
Same journal

Serum Activin A Level and 1-Year Mortality in Atrial Septal Defect-Associated Pulmonary Artery Hypertension: A Case-Control Study From the COHARD-PH Registry.

International journal of vascular medicine·2026
Same journal

A Sedentary Behaviour Reduction Programme in Patients With Peripheral Arterial Disease: A Mixed-Method Feasibility Study.

International journal of vascular medicine·2026
Same journal

RETRACTION: Purpurogallin, a Natural Phenol, Attenuates High-Mobility Group Box 1 in Subarachnoid Hemorrhage Induced Vasospasm in a Rat Model.

International journal of vascular medicine·2026
Same journal

Endovascular Intervention Among Patients Complicated by Acute Inferior Deep Venous Thrombosis: A Single-Center Retrospective Cohort Study From Vietnam.

International journal of vascular medicine·2026
Same journal

Impact of Body Mass Index on the Outcomes of Intensive Complex Decongestive Therapy for Lower Limb Lymphedema.

International journal of vascular medicine·2026
See all related articles

Related Experiment Video

Updated: Jan 9, 2026

Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow
09:18

Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow

Published on: December 15, 2023

3.4K

Blood flow restricted exercise and vascular function.

Masahiro Horiuchi1, Koichi Okita

  • 1Department of Physiology, Yamanashi Institute of Environmental Sciences, Kami-yoshida 5597, Fuji-yoshida, Yamanashi 4030005, Japan ; Northern Regions, Life long Sports Research Center, Hokusho University, Bunkyoudai 23, Ebetsu, Hokkaido 0698511, Japan.

International Journal of Vascular Medicine
|November 8, 2012
PubMed
Summary
This summary is machine-generated.

Blood flow restriction (BFR) training may enhance muscle strength without impairing vascular function, offering a potential solution to the limitations of aerobic and high-intensity resistance training for cardiovascular health and aging.

More Related Videos

Non-invasive Assessment of Microvascular and Endothelial Function
05:41

Non-invasive Assessment of Microvascular and Endothelial Function

Published on: January 29, 2013

16.6K
Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
09:01

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach

Published on: June 5, 2010

14.6K

Related Experiment Videos

Last Updated: Jan 9, 2026

Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow
09:18

Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow

Published on: December 15, 2023

3.4K
Non-invasive Assessment of Microvascular and Endothelial Function
05:41

Non-invasive Assessment of Microvascular and Endothelial Function

Published on: January 29, 2013

16.6K
Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
09:01

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach

Published on: June 5, 2010

14.6K

Area of Science:

  • Exercise physiology
  • Cardiovascular science
  • Sports medicine

Background:

  • Aerobic training enhances vascular function and prevents cardiovascular disease.
  • High-intensity resistance training can impair vascular function, while moderate-intensity effects are debated.
  • Resistance training is crucial for preventing age-related muscle loss (sarcopenia).

Purpose of the Study:

  • To review the impact of blood flow restriction (BFR) exercise on vascular function.
  • To compare BFR training's vascular effects with aerobic and resistance training.
  • To explore BFR as a method to reconcile conflicting training modalities.

Main Methods:

  • Literature review of studies on BFR exercise and vascular function.
  • Analysis of effects on endothelial function, arterial compliance, and coagulation factors.
  • Comparison with existing data on aerobic and resistance training.

Main Results:

  • BFR training shows potential for muscle hypertrophy and strength gains.
  • Evidence suggests BFR training does not significantly alter arterial compliance or coagulation factors.
  • Inconsistent results exist regarding BFR's impact on endothelial function.

Conclusions:

  • BFR training may offer benefits for muscle strength and hypertrophy.
  • Current evidence suggests BFR training is generally safe for vascular health, though endothelial function requires further investigation.
  • BFR training presents a promising alternative or adjunct to traditional exercise for combating sarcopenia and potentially cardiovascular disease.