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Related Concept Videos

Extrinsic and Intrinsic Pathways of Hemostasis01:20

Extrinsic and Intrinsic Pathways of Hemostasis

Blood clotting or coagulation involves extrinsic and intrinsic pathways, which ultimately merge into the common pathway, forming a fibrin clot.
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which forms a...
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
Coagulation01:09

Coagulation

The coagulation phase is a critical part of the body's process to prevent blood loss following injury to blood vessels. It involves chemical reactions that form a clot to seal the injured area. The clotting process begins shortly after injury, within 15-20 seconds for severe damage and 1-2 minutes for minor injuries.
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
Coagulation01:06

Coagulation

Colloidal solids are solid particles suspended in solution. They are usually negatively charged, attracting a compact primary layer of positively charged ions, which attract more counterions to form an electrical double layer. Electrostatic repulsion between the charged double layers prevents the particles from colliding, stabilizing the colloids. These solids are often undesirable because they can contain toxins that are difficult to remove. Coagulation is a technique that helps aggregate and...
Introduction to Hemostasis01:05

Introduction to Hemostasis

Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...
Disorders of Hemostasis01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.

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Related Experiment Video

Updated: May 17, 2026

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
09:38

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

[Effects of headers on coagulation parameters].

C Raschka1, L Klüglein

  • 1Institut für Sportwissenschaft der Julius-Maximilians-Universität Würzburg. craschka@gmx.de

MMW Fortschritte Der Medizin
|November 9, 2012
PubMed
Summary

Soccer headers may cause micro-trauma, indicated by changes in blood markers. This study found significant differences in leucocyte and thrombocyte counts, suggesting a stress response and activation of coagulation systems after heading drills.

Area of Science:

  • Sports medicine
  • Hematology
  • Biomechanics

Context:

  • Heading a soccer ball is a common action in the sport.
  • Potential for repetitive head impacts raises concerns about player safety.
  • Previous research has explored head injury risks, but specific micro-trauma from heading requires further investigation.

Purpose:

  • To investigate the hypothesis that soccer headers induce measurable micro-trauma.
  • To assess the effects of repetitive heading on blood coagulation parameters.
  • To evaluate physiological responses to heading in a controlled laboratory setting.

Summary:

  • Twenty-two soccer players performed intensive heading drills for eight minutes using a standard ball.
  • Blood samples were analyzed for changes in coagulation parameters, including leucocytes, thrombocytes, fibrinogen, INR, Quick, and activated partial thromboplastin time (aPTT).

More Related Videos

A Novel In vitro Model for Studying the Interactions Between Human Whole Blood and Endothelium
06:27

A Novel In vitro Model for Studying the Interactions Between Human Whole Blood and Endothelium

Published on: November 21, 2014

Related Experiment Videos

Last Updated: May 17, 2026

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
09:38

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

A Novel In vitro Model for Studying the Interactions Between Human Whole Blood and Endothelium
06:27

A Novel In vitro Model for Studying the Interactions Between Human Whole Blood and Endothelium

Published on: November 21, 2014

  • Significant increases in leucocytes and thrombocytes were observed, alongside a significant reduction in aPTT, indicating stress and activation of coagulation systems.
  • Impact:

    • Findings suggest that soccer headers can induce physiological stress and micro-trauma.
    • The study provides objective hematological evidence of the body's response to repetitive heading.
    • Results contribute to understanding the potential long-term health implications for soccer players and inform safety protocols.