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Updated: May 17, 2026
An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
Published on: February 10, 2014
[Experimental study of osseointegration of nHA/BG coating and Bio-Oss in implant defects]
Fei Sun1, Ting-ting Lin, Xiao-ye Yuan
1Department of Prosthodontics, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China. fay13706756211@163.com
Purpose:
To evaluate bone regeneration in defects at titanium implants with nHA/BG coating in conjunction with Bio-Oss.
Methods:
Four mandibular premolars were extracted in 6 Beagle dogs. After 3 months, buccal dehiscence-type defects (2.25 mm×3 mm×4 mm) were surgically created following implant site. The three treatment modalities were randomly allocated: nHA/BG implant/Bio-Oss, nHA/BG implant/blood clot, and mHA implant/Bio-Oss. After 8 and 16 weeks, the dogs were sacrificed respectively. A histomorphometric analysis was performed. The data was analyzed with SPSS 13.0 software package for Student's t test and ANOVA.
Results:
At 8- and 16-week, nHA/BG implant group revealed comparable mean BIC (30% to 18% versus 61% to 53%). However, mHA implant/Bio-Oss group revealed significantly lower mean BIC (21% versus 46%) values than nHA/BG implant/Bio-Oss group.A significant difference was observed for the mean BIC and RA values at 8-week between nHA/BG implant/Bio-Oss group and mHA implant/Bio-Oss group.
Conclusions:
It is concluded that the application of Bio-Oss graft did not seem to interfere with the nHA/BG coating activity, but ensured a stabilization of the newly formed bone for defects.
