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Optimization of Radiochemical Reactions using Droplet Arrays
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Batch-reactor microfluidic device: first human use of a microfluidically produced PET radiotracer

Artem Lebedev1, Reza Miraghaie, Kishore Kotta

  • 1Molecular Imaging Biomarker Research, Siemens Healthcare, 6100 Bristol Pkw, Culver City, California, USA. artem.lebedev@siemens.com

Lab on a Chip
|November 9, 2012
PubMed
Summary

This study introduces the first microfluidic device for producing Fluorine-18 (18F)-labeled radiotracers for clinical research, enabling the first human PET scan with such a tracer.

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
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