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Updated: May 5, 2026

Analysis of Physiologic E-Selectin-Mediated Leukocyte Rolling on Microvascular Endothelium
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Published on: February 11, 2009

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Waking up HSCs: a new role for E-selectin.

Malcolm A S Moore1

  • 1Cell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. m-moore@ski.mskcc.org

Nature Medicine
|November 9, 2012
PubMed
Summary

Hematopoietic stem cells (HSCs) reside in two bone marrow niches. Researchers discovered that E-selectin on endothelial cells in the vascular niche promotes HSC proliferation, clarifying niche function.

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