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Updated: May 17, 2026
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Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors
Published on: February 7, 2018
A novel, selective, and extremely responsive thienyl-based dual fluorogenic probe for tandem superoxide and Hg2+
Atul P Singh1, Dhiraj P Murale, Yonghwang Ha
1Molecular Logic Gate Laboratory, Department of Chemistry, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Republic of Korea.
Dalton Transactions (Cambridge, England : 2003)
|November 9, 2012
Abstract:
Novel, high "turn-on" Hg(2+) and O(2)(-) fluorescence behaviour (∼25-fold) with probes bearing [S(thi)N(py)] and [S(thi)N(py)N(py)] binding receptors, joined by oxidizable sulphides, may involve S-bound transient ROS species; such optical O(2)(-) behaviour operates moderately in neuroblastoma.
