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Updated: May 17, 2026
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JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics
Published on: October 19, 2021
Meat science: From proteomics to integrated omics towards system biology
Angelo D'Alessandro1, Lello Zolla
1Department of Ecological and Biological Sciences, University of Tuscia, Largo dell'Università, snc, 01100 Viterbo, Italy.
Journal of Proteomics
|November 10, 2012
Summary
Proteomics and systems biology approaches enhance understanding of meat quality. Integrated
Area of Science:
- Farm animal science
- Meat science
- Proteomics
- Systems biology
Background:
- Proteins are the primary goal of farm animal production.
- Proteomics aids livestock performance monitoring and meat quality research.
- Muscle to meat conversion involves complex post-mortem biochemical changes.
Purpose of the Study:
- To investigate the molecular basis of meat quality.
- To understand the complex muscle to meat conversion process.
- To explore the role of various factors influencing meat tenderness.
Main Methods:
- Proteomics applied to livestock.
- Systems-wide integrated investigations including metabolomics, transcriptomics, interactomics, phosphoproteomics, and mathematical modeling.
- Complementary use of omics disciplines and systems biology.
Main Results:
- Proteomics monitors in vivo livestock performance (growth, fertility, milk quality).
- Post-mortem muscle proteome alterations reveal complexity of meat conversion.
- Meat tenderness is influenced by genetics, rearing, feeding, handling, and stress.
Conclusions:
- Understanding muscle to meat conversion requires integrated omics approaches.
- Systems biology integration is key to advancing meat quality research.
- Further research using integrated omics will improve understanding of meat conversion.
Related Concept Videos
01:33Proteomics
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
02:02Genomics
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
02:26Protein Networks
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
02:26Protein Networks
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...