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Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
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Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...

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Microfluidic Imaging Flow Cytometry by Asymmetric-detection Time-stretch Optical Microscopy (ATOM)
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Published on: June 28, 2017

Optofluidic imaging: now and beyond.

Yanhui Zhao1, Zackary S Stratton, Feng Guo

  • 1Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.

Lab on a Chip
|November 10, 2012
PubMed
Summary
This summary is machine-generated.

Optofluidics research has advanced micro-scale light manipulation. Recent optofluidic imaging techniques bypass traditional elements, achieving high-resolution 2D and 3D imaging without deficiencies.

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Area of Science:

  • Optics
  • Fluidics
  • Microscopy

Background:

  • Optofluidics has developed micro-scale optical elements like lenses and prisms for on-chip applications.
  • Limitations in existing optofluidic elements have hindered micro-scale imaging applications.

Purpose of the Study:

  • To review recent advancements in optofluidic imaging.
  • To discuss the future potential of optofluidic imaging technologies.

Main Methods:

  • Focus on image capture and composition techniques, rather than optofluidic elements.
  • Demonstration of high-resolution 2D imagery and 3D tomography.

Main Results:

  • Successful high-resolution imaging achieved by avoiding traditional optofluidic elements.
  • Demonstrated capabilities in both 2D imaging and 3D tomography.

Conclusions:

  • Optofluidic imaging is evolving beyond traditional micro-optical elements.
  • Future developments promise enhanced capabilities in micro-scale imaging and tomography.