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Impulsivity, attention, memory, and decision-making among adolescent marijuana users.

Donald M Dougherty1, Charles W Mathias, Michael A Dawes

  • 1Department of Psychiatry, The University of Texas Health Science Center at San Antonio, NRLC MC 7793, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA. doughertyd@uthscsa.edu

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Adolescent marijuana use is linked to significant cognitive deficits, particularly in short-term memory and impulse control. These findings highlight specific areas for intervention in young marijuana users.

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Area of Science:

  • Neuroscience
  • Adolescent Psychology
  • Substance Abuse Research

Background:

  • Adolescent marijuana use is prevalent and may lead to cognitive and behavioral impairments.
  • Previous research often examined cognitive measures individually, lacking a cohesive analysis of multiple domains.
  • This study employed a logistic regression model to analyze multiple cognitive and behavioral measures simultaneously.

Purpose of the Study:

  • To identify unique associations between adolescent marijuana use and cognitive/behavioral domains (attention, memory, decision-making, impulsivity).
  • To control for performance across measures to determine which most strongly differentiate marijuana users from nonusers.
  • To investigate these associations in 14- to 17-year-olds.

Main Methods:

  • Compared marijuana-using adolescents (n=45) with controls (n=48).
  • Utilized logistic regression analyses to assess differences and associations.
  • Controlled for performance across multiple cognitive and behavioral measures.

Main Results:

  • Impaired short-term recall memory was significantly associated with marijuana use.
  • Reduced consequence sensitivity in impulsivity was also linked to marijuana use.
  • These associations remained significant after controlling for other cognitive measures.

Conclusions:

  • This study identified specific cognitive and behavioral impairments most strongly associated with adolescent marijuana use.
  • Deficits in short-term recall memory and consequence sensitivity are key findings.
  • These identified deficits offer potential targets for intervention strategies in at-risk adolescent populations.