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Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...

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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Aggregatibacter aphrophilus endocarditis: a case report.

P Wright1, C Keane, H C Ricketts

  • 1Department of Microbiology, Southern General Hospital, Glasgow, Scotland, UK. pauline.wright2@ggc.scot.nhs.uk

Scottish Medical Journal
|November 10, 2012
PubMed
Summary
This summary is machine-generated.

Aggregatibacter aphrophilus endocarditis can cause embolic stroke and digital infarction. This case highlights successful identification using combined methods, suggesting a tongue lesion as the entry point.

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Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
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Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
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Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Endocarditis, a serious infection of the heart lining, can lead to severe complications.
  • Embolic events, such as stroke and digital infarction, are known risks of infective endocarditis.
  • Accurate identification of causative pathogens is crucial for effective treatment.

Observation:

  • A case of infective endocarditis presenting with embolic stroke and digital infarction is described.
  • The causative agent was identified as Aggregatibacter aphrophilus, a recently renamed bacterium.
  • A benign tongue lesion was suspected as the portal of entry for the oropharyngeal organism.

Findings:

  • Isolation and identification of Aggregatibacter aphrophilus were achieved using a combination of phenotypic and genotypic methods.
  • The patient received six weeks of intravenous ceftriaxone, leading to a good clinical recovery.
  • Despite recovery, the patient will require future cardiac valvular surgery.

Implications:

  • This case underscores the importance of considering Aggregatibacter aphrophilus in endocarditis, especially with embolic phenomena.
  • The successful identification highlights the value of integrating traditional and molecular diagnostic techniques.
  • Early recognition and appropriate antibiotic therapy are vital, though surgical intervention may be necessary for valvular complications.