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[Aplastic anemia probably induced by allopurinol in a patient with renal insufficiency]
1Department of Hematology, Central Hospital of Yamaguchi Prefecture.
[Rinsho Ketsueki] the Japanese Journal of Clinical Hematology
|January 1, 1990
Abstract:
A rare case of aplastic anemia which was considered to be induced by allopurinol was reported. A 48-year-old female had suffered from urolithiasis and chronic renal insufficiency. She was administered allopurinol for hyperuricemia for 4 months, and subsequently developed severe pancytopenia and bone marrow suppression. After stopping of allopurinol administration, she was administered prednisolone but died of gastro-intestinal tract bleeding and sepsis on the 21th hospital day, without hematological recovery.