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[Bone mineral determination using dual energy X-ray absorptiometry (DEXA)]
M Fukunaga1, T Tomomitsu, R Morita
1Department of Nuclear Medicine, Kawasaki Medical School.
Rinsho Hoshasen. Clinical Radiography
|January 1, 1990
Summary
Dual energy X-ray absorptiometry (DEXA) accurately measures bone mineral density in appendicular and axial skeleton. Findings reveal earlier and more severe bone loss in women, particularly in the vertebrae, aiding osteoporosis fracture risk assessment.
Area of Science:
- Gerontology
- Orthopedics
- Radiology
Background:
- Aging leads to bone loss, increasing fracture risk.
- Osteoporosis assessment requires accurate bone mineral density (BMD) measurement.
- Differential bone loss patterns exist between cortical and trabecular bone.
Purpose of the Study:
- To accurately quantify appendicular and axial bone mineral density using DEXA.
- To compare bone loss patterns in males and females with aging.
- To evaluate the utility of BMD in predicting vertebral fracture risk.
Main Methods:
- Utilized dual energy X-ray absorptiometry (DEXA) for BMD assessment.
- Employed Aloka DCS-600 for radius (cortical bone) and Hologic QDR-1000 for lumbar vertebrae (trabecular bone).
- Calculated vertebral fracture risk by comparing individual BMD to peak bone mass.
Main Results:
- Bone loss with aging occurred earlier and was more pronounced in females than males.
- Lumbar vertebrae showed more significant bone loss compared to the radius.
- BMD percentiles correlate with vertebral fracture rates.
Conclusions:
- DEXA provides accurate and precise BMD assessment for both appendicular and axial skeleton.
- Age-related bone loss differs between sexes and bone types.
- BMD measurements are valuable for osteoporosis assessment and identifying patients at high risk for fractures.