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Published on: February 14, 2017
A novel approach to the diagnosis of stress-induced cardiomyopathy
Jered Haynor1, Christopher Colombo, Sean Javaheri
1Department of Medicine, Dwight D. Eisenhower Army Medical Center, Fort Gordon, GA 30905-5741, USA. jered.haynor@amedd.army.mil
Insights
Stress-induced cardiomyopathy, a recognized diagnosis, can mimic acute myocardial infarction. This case highlights rapid recovery of heart function after diagnosis and treatment for this condition.
Area of Science:
- Cardiology
- Cardiovascular Medicine
- Clinical Case Reports
Background:
- Stress-induced cardiomyopathy (SIC), also known as Takotsubo cardiomyopathy, is increasingly recognized.
- It accounts for 2-3% of acute anterior myocardial infarction presentations.
- SIC diagnosis requires careful differentiation from obstructive coronary artery disease.
Observation:
- A 68-year-old male presented with dyspnea and chest pain post-operation.
- ECG showed ST-segment elevation, and cardiac biomarkers were elevated.
- Echocardiography revealed significant left ventricular dysfunction with apical akinesia and basilar hyperkinesis.
Findings:
- Coronary angiography excluded obstructive coronary artery disease.
- The patient was diagnosed with stress-induced cardiomyopathy.
- Treatment followed standard systolic heart failure guidelines.
Implications:
- This case underscores the importance of considering SIC in patients with acute cardiac symptoms, especially post-stress.
- Prompt diagnosis and management led to rapid clinical and echocardiographic improvement.
- Understanding SIC's distinct pathophysiology is crucial for appropriate patient care and prognosis.
Abstract:
Stress-induced cardiomyopathy is becoming a more commonly recognized diagnosis, accounting for 2% to 3% of patients presenting with signs and symptoms of acute anterior myocardial infarction. We present the case of a 68-year-old man with dyspnea 9 days after an unrelated operation. After hospital admission, he complained of chest pain, and an electrocardiogram demonstrated ST-segment elevation in the anterolateral and inferior leads, ST-segment depression in lead aVR, and an absence of ST-segment changes in lead V(1). Cardiac biomarker levels were elevated. Transthoracic echocardiography demonstrated a left ventricular ejection fraction of 30% to 40%, basilar hyperactivity, apical dyskinesia, and distal inferior and anterior akinesia. Cardiac catheterization did not reveal any culprit obstructive lesion. He received a diagnosis of stress-induced cardiomyopathy and was treated according to established recommendations for systolic heart failure. His cardiac biomarkers returned to normal, and a repeated transthoracic echocardiogram 3 days later revealed nearly complete resolution of myocardial wall-motion abnormalities.
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