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Updated: May 17, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Taste and temperature in swallowing transit time after stroke
Paula C Cola1, Ana R Gatto, Roberta G da Silva
1Department of Surgery, Botucatu Medical School, UNESP, Botucatu, Brazil.
The sequence of taste and temperature stimuli significantly impacts swallowing in stroke survivors. A sour-cold stimulus, when presented non-randomly, shortened pharyngeal transit time, suggesting its therapeutic potential for dysphagia.
Area of Science:
- Neurology
- Gastroenterology
- Speech-Language Pathology
Background:
- Oropharyngeal dysphagia is a common post-stroke complication.
- Taste and temperature stimuli are utilized in dysphagia rehabilitation.
- The impact of stimulus sequence on swallowing biomechanics requires further investigation.
Purpose of the Study:
- To investigate the influence of stimulus sequence on pharyngeal transit time in stroke patients.
- To compare the effects of non-randomized versus randomized stimulus presentation.
Main Methods:
- 60 stroke patients with dysphagia were divided into two groups.
- Group 1 received a non-randomized sequence of stimuli (natural, cold, sour, sour-cold).
- Group 2 received a randomized sequence of stimuli.
- Videofluoroscopic swallowing studies measured pharyngeal transit time.
Main Results:
- The non-randomized group showed significantly shorter pharyngeal transit time with the sour-cold stimulus.
- No significant difference in pharyngeal transit time was observed between stimuli in the randomized group.
Conclusions:
- Stimulus sequence affects pharyngeal transit time in post-stroke dysphagia.
- The sour-cold stimulus may serve as a therapeutic tool for dysphagic stroke patients, particularly when presented non-randomly.
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