Related Experiment Video
Updated: May 17, 2026

Retrograde Perfusion and Filling of Mouse Coronary Vasculature as Preparation for Micro Computed Tomography Imaging
Published on: February 10, 2012
How new imaging techniques can aid in defining the cardiovascular profile of the high-risk patient
S Bosi1, A Barbieri, M Baldelli
1Maria Cecilia Hospital, Cotignola, Italia.
Insights
Cardiovascular prevention strategies are evolving with new data. Imaging techniques like MRI and coronary CT are crucial for assessing atherosclerotic vascular disease and defining cardiovascular risk.
Area of Science:
- Cardiology and Cardiovascular Disease Research
- Medical Imaging and Diagnostics
Background:
- Cardiovascular prevention has rapidly evolved, necessitating frequent updates due to accumulating data.
- Coronary obstruction changes, linked to plasma lipids, have been observed via angiography.
- Hypertension guidelines have shifted, emphasizing organ damage assessment for prognosis.
Purpose of the Study:
- To highlight the evolving landscape of cardiovascular prevention.
- To underscore the importance of imaging in assessing atherosclerotic vascular disease.
- To identify advanced imaging modalities for cardiovascular risk assessment.
Main Methods:
- Review of studies utilizing angiography to assess coronary lesion changes.
- Analysis of updated hypertension guidelines focusing on organ damage.
- Evaluation of Magnetic Resonance (MRI) and coronary computed tomography (coro CT) for cardiovascular assessment.
Main Results:
- Angiography studies demonstrate progression, stabilization, or regression of coronary lesions.
- Cardiovascular risk definition now incorporates documentation and quantification of atherosclerotic plaques.
- MRI and coro CT show promise in evaluating heart and large vessel conditions.
Conclusions:
- The assessment of atherosclerotic vascular disease extent is critical for defining cardiovascular risk.
- Advanced imaging techniques like MRI and coronary CT are key for future cardiovascular risk stratification.
Abstract:
Cardiovascular prevention has been developed in the last eight years producing an ever increasing amount of data requiring frequent updating. Studies using angiography to determine change in coronary obstruction have indicated progression, stabilization, or regression of coronary lesions associated with changes in plasma lipids and lipoproteins. Moreover, the guidelines on arterial hypertension published in 2007 listed the risk factors affecting prognosis but even by 2009 an update modified not only the list of risks, but even the philosophy behind the thought process which introduced as essential element in the prognosis of hypertension the ascertained existence of a damaged organ. Thus, the documentation of atherosclerotic vascular disease (plaques) and the quantification of its extension in the arterial tree became a determinant in the definition of cardiovascular risk. Magnetic Resonance (MRI) and coronary computed tomography (coro CT) applied to the heart and large vessels are the most promising methods.
Related Concept Videos
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Imaging Studies for Cardiovascular System IV: CMRI

