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Updated: May 17, 2026
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Transvaginal Mesh Insertion in the Ovine Model
Published on: July 27, 2017
Risk factors for mesh extrusion after prolapse surgery: a case-control study
Nazanin Ehsani1, Mohamed A Ghafar, Danielle D Antosh
1Department of Obstetrics and Gynecology, St. Luke's Hospital and Health Network, Bethlehem, PA, USA. Nazy30@gmail.com
Female Pelvic Medicine & Reconstructive Surgery
|November 13, 2012
Summary
Concomitant hysterectomy increases the risk of mesh extrusion after pelvic organ prolapse repair using abdominal sacral colpopexy (ASC) or vaginal mesh procedures (VMP). This finding aids in preoperative counseling for women undergoing these surgeries.
Area of Science:
- Urogynecology
- Pelvic reconstructive surgery
- Surgical outcomes research
Background:
- Pelvic organ prolapse (POP) repair frequently utilizes synthetic mesh.
- Mesh extrusion is a known complication, impacting patient quality of life.
- Identifying risk factors is crucial for improving surgical outcomes.
Purpose of the Study:
- To determine risk factors for mesh extrusion following abdominal sacral colpopexy (ASC) and vaginal mesh procedures (VMP).
- To provide data for enhanced patient counseling and surgical planning.
Main Methods:
- Multicenter case-control study (2006-2009).
- Cases: mesh extrusion post-ASC or VMP.
- Controls: matched patients without extrusion.
- Conditional logistic regression analysis.
Main Results:
- Concomitant hysterectomy significantly increased mesh extrusion risk in both ASC (aOR 3.18) and VMP (aOR 3.72) groups.
- No significant association found for age, race, menopausal status, comorbidities, or smoking.
- 84 cases and 252 controls were analyzed.
Conclusions:
- Concomitant hysterectomy is a significant risk factor for mesh extrusion after POP repair with mesh.
- This knowledge is vital for informed preoperative discussions with patients.
- Further research may explore mechanisms linking hysterectomy to extrusion.
