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An update on chymopapain for treating lumbar disc ruptures
1Division of Orthopedic Surgery, Washington University Medical Center, St. Louis, Missouri 63110.
Missouri Medicine
|March 1, 1990
Summary
Chymopapain injections offer a promising, less invasive alternative to surgery for treating ruptured discs. This enzyme aids in disc lysis, potentially improving patient outcomes.
Area of Science:
- Neurosurgery
- Pharmacology
- Biochemistry
Background:
- Degenerative disc disease is a common cause of back pain.
- Surgical interventions carry risks and may not be suitable for all patients.
Purpose of the Study:
- To evaluate the efficacy of chymopapain as a non-surgical treatment for ruptured discs.
- To assess chymopapain's potential as an alternative to traditional surgical procedures.
Main Methods:
- The study involved the author's clinical experience using chymopapain.
- Chymopapain was administered for the lysis of ruptured intervertebral discs.
Main Results:
- Chymopapain demonstrated effectiveness in achieving disc lysis.
- The drug proved to be a viable alternative to surgical intervention.
Conclusions:
- Chymopapain represents a valuable non-surgical option for managing ruptured discs.
- Further research may solidify its role in conservative spine care.

