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Updated: May 17, 2026

Processing of Human Cardiac Tissue Toward Extracellular Matrix Self-assembling Hydrogel for In Vitro and In Vivo Applications
Published on: December 4, 2017
Use of extracellular matrix materials in patients with endocarditis
Simon Harald Sündermann1, Héctor Rodriguez Cetina Biefer1, Maximilian Y Emmert1
1Department of Cardiovascular Surgery, University Hospital Zurich, Zürich, Switzerland.
Abstract:
Tissue replacement is sometimes necessary during surgery for endocarditis. Commonly used materials are Dacron, expanded polytetrafluoroethlyene, or bovine pericardium. Those materials have no potential for bioresorption and cannot restore regional functionality. Extracellular matrices became available lately as patch material. Here we present two cases of patients with endocarditis. CorMatrix ECM (CorMatrix Cardiovascular, Inc., Atlanta, Georgia, United States) was used to repair intracardiac structures with good results in follow-up up to 3 months. CorMatrix ECM may be an adequate alternative to foreign material for patients with endocarditis.
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The Extracellular Matrix
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