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Related Experiment Videos

Steroid-responsive electromyographic abnormalities in polymyalgia rheumatica.

M B Bromberg1, P D Donofrio, B M Segal

  • 1Department of Neurology, University of Michigan Medical Center, Ann Arbor 48109-0032.

Muscle & Nerve
|February 1, 1990
PubMed
Summary
This summary is machine-generated.

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Polymyalgia rheumatica patients may show nerve damage on electrodiagnostic studies. Steroid treatment improved both clinical symptoms and nerve function, suggesting a steroid-responsive arteritis.

Area of Science:

  • Neurology
  • Rheumatology
  • Clinical Electrophysiology

Background:

  • Electrodiagnostic studies are frequently used in polymyalgia rheumatica (PMR) to assess muscle symptoms.
  • These studies are typically normal in PMR, with few documented cases of electromyographic abnormalities.

Observation:

  • This report details two patients diagnosed with polymyalgia rheumatica.
  • Both patients presented with electrodiagnostic findings indicative of diffuse denervation.

Findings:

  • Following corticosteroid therapy, both patients demonstrated significant clinical improvement.
  • Electromyographic studies also showed marked improvement after steroid treatment.

Implications:

  • The findings suggest a potential link between polymyalgia rheumatica and nerve damage.

Related Experiment Videos

  • A hypothesized steroid-responsive microvascular arteritis causing ischemic axonal damage is proposed.
  • This could indicate a novel pathophysiological mechanism in a subset of PMR patients.