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Genome sequence of Stenotrophomonas maltophilia S028, an isolate harboring the AmpR-L2 resistance module

Shiping Song1, Xitong Yuan, Shiwei Liu

  • 1PLA 307 Hospital, Academy of Military Medical Science, Beijing, People's Republic of China.

Journal of Bacteriology
|November 13, 2012
PubMed

Insights

Multidrug-resistant Stenotrophomonas maltophilia causes hospital infections due to beta-lactamase enzymes. This study presents the genome sequence of an S. maltophilia isolate (S028) carrying the common AmpR-L2 beta-lactamase module.

Area of Science:

  • Microbiology
  • Genomics
  • Infectious Diseases

Background:

  • Multidrug-resistant Stenotrophomonas maltophilia is a significant pathogen in healthcare settings.
  • Beta-lactamase production is a primary mechanism for S. maltophilia's resistance.
  • The AmpR-L2 module, encoding L2 beta-lactamase, is frequently found in S. maltophilia.

Purpose of the Study:

  • To announce the genome sequence of a Stenotrophomonas maltophilia isolate.
  • To characterize an isolate harboring the prevalent AmpR-L2 module.

Main Methods:

  • Genome sequencing of S. maltophilia isolate S028.

Main Results:

  • The genome sequence of S. maltophilia isolate S028 was successfully obtained.
  • S028 harbors the AmpR-L2 module, a common beta-lactamase determinant.

Conclusions:

  • The availability of the S028 genome sequence provides a valuable resource for studying S. maltophilia resistance mechanisms.
  • Further research can utilize this genome data to understand the AmpR-L2 module's role in antimicrobial resistance.

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