Diffusion tensor metrics as biomarkers in Alzheimer's disease

Julio Acosta-Cabronero1, Stephanie Alley, Guy B Williams

  • 1Cognition, Memory and Language Group, Neurology Unit, Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom. jac@cantab.net

Plos One
|November 13, 2012
PubMed
Summary

Diffusion tensor imaging (DTI) shows potential for Alzheimer's disease biomarkers. Early changes in axial/mean diffusivity are state-specific, while radial diffusivity/fractional anisotropy track disease progression and severity.