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Acute renal failure due to pyelonephritis.
W B Lorentz1, S Iskandar, M C Browning
1Department of Pediatrics, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, N.C.
Nephron
|January 1, 1990
Summary
Acute pyelonephritis can cause acute kidney injury in children. Prompt antibiotic treatment is vital for recovery, as this condition is an uncommon cause of kidney failure in pediatric patients.
Area of Science:
- Pediatric Nephrology
- Infectious Diseases
Background:
- Acute pyelonephritis, a kidney infection, is a common pediatric illness.
- Acute kidney injury (AKI) in children necessitates prompt diagnosis and management.
Observation:
- A 3-year-old boy presented with acute renal failure secondary to acute pyelonephritis.
- Renal biopsy revealed acute interstitial inflammation with neutrophils and macrophages, glomerulitis, and capillary tuft thrombosis.
Findings:
- The patient required peritoneal dialysis for acute renal failure.
- Complete recovery of renal function was achieved following treatment.
Implications:
- Acute pyelonephritis is an infrequent but serious cause of AKI in the pediatric population.
- Early antimicrobial therapy is critical for favorable outcomes in pediatric patients with pyelonephritis-associated AKI.