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Updated: May 16, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Multiple finger nodules and an erythematous rash - a case study
Jacinto Orgaz-Molina1, Maria Salazar-Nievas, Maria Carmen Orgaz-Molina
1Department of Dermatology, San Cecilio University Hospital, Granada, Spain. jacinto_orgaz@hotmail.com
Case Study:
A previously well male, 18 years of age, from a rural community, presented with three painful, itchy nodules on the fingers of his left hand, which had been present for 1 week. He had been prescribed amoxicillin clavulanate but presented again when there was no improvement after 4 days of taking antibiotics. Examination revealed three erythematous and umbilicated nodules without any halo, but with a central depression with exudate (Figure 1a). No specific treatment was instituted at this visit. One week later the patient re-presented with new erythematous lesions on the palms and dorsum of his hands. The original three lesions had improved and were drier than previously (Figure 1b, c). The new lesions disappeared after 2 weeks and the original lesions after 4 weeks, without any other treatment.
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