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Full circle-old drugs prove more beneficial than newer agents for schizophrenia: a case report
Michael A Veronin1, Kendra Colson, Michael E Roffman
1Texas A&M Health Science Center, Rangel College of Pharmacy, Pharmaceutical Sciences, Kingsville, Texas 78363–8202, USA. veronin@pharmacy.tamhsc.edu
Abstract:
A 55-year-old female with a diagnosis of schizophrenia currently resides in an assisted living facility in a large metropolitan suburb. For approximately 25 years, the patient was relegated to a life of poor symptom control and social adjustment, largely due to nonadherence, relapse, and rehospitalization. The patient experienced a trial-and-error approach to drug therapy, which resulted in reliance on the older or first generation agents for symptom improvement. This case supports the assertion that the second-generation or atypical antipsychotics used to treat schizophrenia are no better than older drugs in terms of efficacy or tolerability.
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