Related Experiment Video
Updated: May 16, 2026

Hyperglycemic Clamp and Hypoglycemic Clamp in Conscious Mice
Published on: January 26, 2024
The carpal pad as an alternative sampling site for blood glucose testing in dogs
S Borin-Crivellenti1, L Z Crivellenti, M Tinucci-Costa
1Clinics and Surgery of Small Animals, Via de Acesso Professor Paulo Donato Castellani, Universidade Estadual Paulista (UNESP), Jaboticabal, São Paulo, Brazil.
Objective:
To investigate the feasibility and validity of sampling blood from the carpal pad in hospitalised healthy and diabetic dogs.
Methods:
The carpal pad was compared to the ear as a sampling site in 60 dogs (30 healthy and 30 diabetic dogs).
Results:
Lancing the pads was very well tolerated. The average glucose concentrations in blood samples obtained from the ears and carpal pads exhibited a strong positive correlation (r = 0·938) and there were no significant differences between them (P = 0·914). In addition, 98·3% of the values obtained were clinically acceptable when assessed by the error grid analysis.
Clinical Significance:
The carpal pad is a good alternative sampling site for home monitoring, especially in animals with a soft and/or light-coloured pad.

