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Assessment of atrial electromechanical delay in children with acute rheumatic fever
Murat Ciftel1, Ozlem Turan1, Ayşe Simşek1
1Department of Pediatric Cardiology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.
Insights
Acute rheumatic fever patients show prolonged P-wave dispersion and interatrial electromechanical delay. Left atrial enlargement may contribute to these changes, increasing arrhythmia risk.
Area of Science:
- Cardiology
- Electrophysiology
- Rheumatology
Background:
- Acute rheumatic fever (ARF) can affect the heart, potentially leading to atrial arrhythmias.
- Left atrial enlargement is a known complication of ARF and may influence cardiac conduction.
- Assessing atrial electromechanical delay and P-wave dispersion can provide insights into atrial function in ARF.
Purpose of the Study:
- To investigate atrial electromechanical delay and P-wave dispersion in patients with acute rheumatic fever.
- To explore the relationship between left atrial size and these electrophysiological parameters in ARF.
Main Methods:
- Compared 48 ARF patients with 40 healthy volunteers.
- Evaluated M-mode echocardiographic parameters, interatrial and intra-atrial electromechanical delay, and P-wave dispersion.
- Analyzed correlations between left atrium diameter, P-wave dispersion, and interatrial electromechanical delay.
Main Results:
- ARF patients exhibited significantly higher maximum P-wave duration, P-wave dispersion, and interatrial electromechanical delay than controls.
- No significant difference in intra-atrial electromechanical delay was observed between groups.
- Positive correlations found between left atrium diameter and P-wave dispersion (r=0.524) and interatrial electromechanical delay (r=0.351) in ARF patients.
Conclusions:
- Acute rheumatic fever is associated with prolonged P-wave dispersion and interatrial electromechanical delay.
- Left atrial enlargement is a potential underlying factor contributing to these electrophysiological abnormalities in ARF.
- These findings highlight potential mechanisms for increased atrial arrhythmia risk in ARF.
Purpose:
There may be an increase in the risk of atrial arrhythmia due to left atrial enlargement and the influence on conduction system in acute rheumatic fever. The aim of this study is to investigate atrial electromechanical delay and P-wave dispersion in patients with acute rheumatic fever.
Patients:
A total of 48 patients diagnosed with acute rheumatic fever and 40 volunteers of similar age, sex, and body mass index were included in the study. The study groups were compared for M-mode echocardiographic parameters, interatrial electromechanical delay, intra-atrial electromechanical delay, and P-wave dispersion.
Results:
Maximum P-wave duration, P-wave dispersion, and interatrial electromechanical delay were significantly higher in patients with acute rheumatic fever compared with the control group (p < 0.001). However, there was no difference in terms of intra-atrial electromechanical delay (p > 0.05). For patients with acute rheumatic fever, a positive correlation was identified between the left atrium diameter and the P-wave dispersion and interatrial electromechanical delay (r = 0.524 and p < 0.001, and r = 0.351 and p = 0.014, respectively). Furthermore, an important correlation was also identified between the P-wave dispersion and the interatrial electromechanical delay (r = 0.494 and p < 0.001).
Conclusion:
This study shows the prolongation of P-wave dispersion and interatrial electromechanical delay in acute rheumatic fever. Left atrial enlargement can be one of the underlying reasons for the increase in P-wave dispersion and interatrial electromechanical delay.
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