Assessment of atrial electromechanical delay in children with acute rheumatic fever

Murat Ciftel1, Ozlem Turan1, Ayşe Simşek1

  • 1Department of Pediatric Cardiology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.

Cardiology in the Young
|November 14, 2012
PubMed

Insights

Acute rheumatic fever patients show prolonged P-wave dispersion and interatrial electromechanical delay. Left atrial enlargement may contribute to these changes, increasing arrhythmia risk.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Rheumatology

Background:

  • Acute rheumatic fever (ARF) can affect the heart, potentially leading to atrial arrhythmias.
  • Left atrial enlargement is a known complication of ARF and may influence cardiac conduction.
  • Assessing atrial electromechanical delay and P-wave dispersion can provide insights into atrial function in ARF.

Purpose of the Study:

  • To investigate atrial electromechanical delay and P-wave dispersion in patients with acute rheumatic fever.
  • To explore the relationship between left atrial size and these electrophysiological parameters in ARF.

Main Methods:

  • Compared 48 ARF patients with 40 healthy volunteers.
  • Evaluated M-mode echocardiographic parameters, interatrial and intra-atrial electromechanical delay, and P-wave dispersion.
  • Analyzed correlations between left atrium diameter, P-wave dispersion, and interatrial electromechanical delay.

Main Results:

  • ARF patients exhibited significantly higher maximum P-wave duration, P-wave dispersion, and interatrial electromechanical delay than controls.
  • No significant difference in intra-atrial electromechanical delay was observed between groups.
  • Positive correlations found between left atrium diameter and P-wave dispersion (r=0.524) and interatrial electromechanical delay (r=0.351) in ARF patients.

Conclusions:

  • Acute rheumatic fever is associated with prolonged P-wave dispersion and interatrial electromechanical delay.
  • Left atrial enlargement is a potential underlying factor contributing to these electrophysiological abnormalities in ARF.
  • These findings highlight potential mechanisms for increased atrial arrhythmia risk in ARF.
Abstract

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