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Intracranial Orthotopic Allografting of Medulloblastoma Cells in Immunocompromised Mice
Published on: October 3, 2010
Primary intracerebral myeloid sarcoma
Meral Gunaldi1, Ismail O Kara, Berna B Duman
1Department of Medical Oncology, Faculty of Medicine, University of Cukurova, Saricam-Adana, Turkey. mgunaldi@cu.edu.tr
Background:
Myeloid sarcoma rarely presents in the absence of systemic myeloid disease.
Case Report:
In this study, we present a case of intracerebral myeloid sarcoma with no diagnosis of any hematological disease in a 22-year-old male patient in whom brain magnetic resonance image revealed a meningioma. However, biopsy showed myeloid sarcoma. No myeloid disease was determined. The mass disappeared following 8 cycles of chemotherapy. In the literature, we determined only 8 similar cases cited between 1970 and 2011.
Conclusion:
Intracerebral myeloid sarcoma has currently no standard treatment and may be confused with a primary brain disease. Chemotherapy and/or radiotherapy are the most viable and widely used treatment modalities. Potential occurrence of hematological disease should also be closely followed due to conversion risks.
