Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Animal Mitochondrial Genetics

Animal Mitochondrial Genetics

Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...

Mitochondria

Mitochondria

Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...

Cell Specific Gene Expression

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Enhanced expression of proteins involved in energy production and transfer in breast muscle of pedigree male broilers exhibiting high feed efficiency.

Poultry science·2017

Same author

Surface wetting strategy prevents acute heat exposure-induced alterations of hypothalamic stress- and metabolic-related genes in broiler chickens.

Journal of animal science·2017

Same author

Cell bioenergetics in Leghorn male hepatoma cells and immortalized chicken liver cells in response to 4-hydroxy 2-nonenal-induced oxidative stress.

Poultry science·2014

Same author

Gene expression in breast muscle associated with feed efficiency in a single male broiler line using a chicken 44K microarray. II. Differentially expressed focus genes.

Poultry science·2012

Same author

Gene expression in breast muscle associated with feed efficiency in a single male broiler line using a chicken 44K oligo microarray. I. Top differentially expressed genes.

Poultry science·2011

Same author

Improved hatchability and posthatch performance in turkey poults receiving a dextrin-iodinated casein solution in ovo.

Poultry science·2010

Search research articles

Related Experiment Video

Updated: May 16, 2026

A Faster, High Resolution, mtPA-GFP-based Mitochondrial Fusion Assay Acquiring Kinetic Data of Multiple Cells in Parallel Using Confocal Microscopy

A Faster, High Resolution, mtPA-GFP-based Mitochondrial Fusion Assay Acquiring Kinetic Data of Multiple Cells in Parallel Using Confocal Microscopy

Published on: July 20, 2012

Cell Biology Symposium: feed efficiency: mitochondrial function to global gene expression.

W Bottje¹, B-W Kong

¹Department of Poultry Science, Center of Excellence for Poultry Science, Division of Agriculture, University of Arkansas, Fayetteville 72701, USA. wbottje@uark.edu

Journal of Animal Science

|November 14, 2012

Summary

Understanding feed efficiency (FE) in poultry is key for protein production. High FE broilers show increased anabolic and energy-sensing gene expression, while low FE broilers exhibit upregulation of cytoskeletal and stress-related genes, suggesting oxidative stress modulation.

More Related Videos

Labelling and Visualization of Mitochondrial Genome Expression Products in Baker's Yeast Saccharomyces cerevisiae

Labelling and Visualization of Mitochondrial Genome Expression Products in Baker's Yeast Saccharomyces cerevisiae

Published on: April 11, 2021

Studying Mitochondrial Structure and Function in Drosophila Ovaries

Studying Mitochondrial Structure and Function in Drosophila Ovaries

Published on: January 4, 2017

Related Experiment Videos

Last Updated: May 16, 2026

A Faster, High Resolution, mtPA-GFP-based Mitochondrial Fusion Assay Acquiring Kinetic Data of Multiple Cells in Parallel Using Confocal Microscopy

A Faster, High Resolution, mtPA-GFP-based Mitochondrial Fusion Assay Acquiring Kinetic Data of Multiple Cells in Parallel Using Confocal Microscopy

Published on: July 20, 2012

Labelling and Visualization of Mitochondrial Genome Expression Products in Baker's Yeast Saccharomyces cerevisiae

Labelling and Visualization of Mitochondrial Genome Expression Products in Baker's Yeast Saccharomyces cerevisiae

Published on: April 11, 2021

Studying Mitochondrial Structure and Function in Drosophila Ovaries

Studying Mitochondrial Structure and Function in Drosophila Ovaries

Published on: January 4, 2017

Area of Science:

Animal Genomics
Molecular Biology
Poultry Science

Background:

Feed efficiency (FE) is crucial for sustainable animal protein production.
Understanding the genetic basis of FE can improve livestock breeding.
Gene expression in muscle tissue plays a significant role in metabolic processes.

Purpose of the Study:

To investigate the relationship between gene expression and feed efficiency in broiler chickens.
To identify specific genes, networks, and pathways associated with high and low FE phenotypes.
To elucidate the cellular mechanisms underlying differences in feed efficiency.

Main Methods:

Global RNA transcription analysis using an Agilent 44K chicken oligoarray.
Comparison of gene expression profiles in breast muscle from high-FE and low-FE broiler phenotypes.
Ingenuity Pathway Analysis (IPA) to identify associated biological pathways and networks.

Main Results:

782 differentially expressed genes (P < 0.05) were identified between high- and low-FE broilers.
High-FE phenotype showed increased expression of genes involved in signal transduction, anabolism, and energy sensing.
Low-FE phenotype exhibited upregulation of genes related to actin-myosin filaments, cytoskeletal structure, and stress response.

Conclusions:

The high-FE phenotype is associated with enhanced cellular growth and development pathways.
The low-FE phenotype appears to be influenced by oxidative stress and associated gene expression.
These findings provide insights into the molecular basis of feed efficiency in poultry muscle.