Related Experiment Video
Updated: May 12, 2026

Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
Trigohowilols A-G, degraded diterpenoids from the stems of Trigonostemon howii
Gui-Hua Tang1, Yu Zhang, Chun-Mao Yuan
1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201, Yunnan, People's Republic of China.
Abstract:
Two new degraded diterpenoids, trigohowilols A (1) and B (2), four new heterodimers, trigohowilols C-F (3-6), one new homodimer, trigohowilol G (7), and three known degraded diterpenoids (8-10) were isolated from the methanol extract of the stems of Trigonostemon howii. Compounds 1-7 were evaluated for their cytotoxic activity against five human tumor cell lines by an MTT assay, and trigohowilols E (5) and F (6) exhibited inhibitory activity with IC50 values ranging from 2.33 to 12.57 μM. Moreover, compounds 1-6 showed weak antimicrobial activities (MIC values: 6.25-25 μg/mL) against Staphylococcus aureus, Pseudomonas aeruginosa, MRSA 92(#), and MRSA 98(#) using a 2-fold dilution method.
More Related Videos
Related Concept Videos
Stereoisomerism of Cyclic Compounds
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide
Drugs that Stabilize Microtubules
Preparation of Diols and Pinacol Rearrangement
The reaction begins with transferring a proton from the acid catalyst to one of the hydroxyl groups, producing an oxonium ion.
Trigonometry of Right Triangles
Trigonometric Identities III

