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Updated: May 16, 2026
08:49
Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Long-term outcome after extensive intestinal resection for chronic radiation enteritis
Aurelien Amiot1, Francisca Joly, Jérémie H Lefevre
1Department of Gastroenterology and Nutrition Support, Beaujon Hospital, APHP, Clichy, France. aurelien.amiot@bjn.aphp.fr
Summary
This study on chronic radiation enteritis patients with short bowel syndrome found good survival rates, influenced by comorbidities. Many patients were successfully weaned off home parenteral nutrition.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Radiation Oncology
Background:
- Chronic radiation enteritis management is challenging, especially concerning short bowel syndrome.
- Risk stratification is crucial for optimizing patient outcomes.
Purpose of the Study:
- To evaluate survival and home parenteral nutrition (HPN) dependence in patients with chronic radiation enteritis and short bowel syndrome.
- To identify factors influencing survival and HPN dependence.
Main Methods:
- Retrospective study of 107 patients with chronic radiation enteritis and short bowel syndrome (1980-2009).
- Univariate and multivariate analyses were used to assess survival and HPN dependence.
Main Results:
- 10-year survival probability was 44.5%. Factors decreasing survival included residual neoplastic disease, ASA score >3, and age >60 at diagnosis.
- 3-year HPN dependence probability was 43%. Factors decreasing dependence included residual small bowel length >100 cm, adaptive hyperphagia, and absence of a stoma.
Conclusions:
- Survival in diffuse chronic radiation enteritis with short bowel syndrome is good, primarily affected by comorbidities.
- Nearly two-thirds of patients could be weaned from HPN, indicating potential for improved quality of life.
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