Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Endocannabinoid cerebrospinal fluid levels in migraine and its relation to symptoms of depression.

Cephalalgia : an international journal of headache·2026

Same author

Placebo or active comparator in chronic migraine trials: Balancing evidence and practicality.

Cephalalgia : an international journal of headache·2026

Same author

Efficacy and safety of eptinezumab in adults with chronic migraine and medication-overuse headache who also received patient education: 24-week results of the randomized RESOLUTION trial.

The journal of headache and pain·2026

Same author

Aortic stiffness and cardiac function in middle-aged women with ischemic stroke with and without migraine.

BMC neurology·2026

Same author

Benefits of eptinezumab on patient-reported disease burden and health-related quality of life in adults with chronic migraine and medication-overuse headache: Results from the placebo-controlled RESOLUTION trial.

Cephalalgia : an international journal of headache·2026

Same author

Visually-induced hemodynamic response and white matter hyperintensities in middle-aged women with ischemic stroke or migraine with aura.

Cephalalgia : an international journal of headache·2026

Search research articles

Related Experiment Video

Updated: May 12, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Structural brain changes in migraine.

Inge H Palm-Meinders¹, Hille Koppen, Gisela M Terwindt

¹Department of Radiology, Leiden University Medical Center, the Netherlands.

|November 15, 2012

Summary

This summary is machine-generated.

Women with migraine showed increased deep white matter hyperintensities on MRI scans over 9 years. Migraine was not associated with other brain lesion progression in women or any lesions in men.

More Related Videos

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

Published on: November 1, 2024

Related Experiment Videos

Last Updated: May 12, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

Published on: November 1, 2024

Area of Science:

Neurology
Neuroimaging
Epidemiology

Background:

Previous studies suggest a link between migraine and brain lesions.
Magnetic resonance imaging (MRI) has identified ischemic lesions in individuals with migraine.

Purpose of the Study:

To investigate the incidence of brain lesions in men and women with migraine over 9 years.
To determine if migraine frequency correlates with lesion progression.
To assess the association between brain lesion progression and cognitive decline.

Main Methods:

A prospective, population-based observational study followed a cohort of Dutch participants with migraine and a control group.
Participants underwent repeat MRI scans after 9 years to assess progression of deep white matter hyperintensities, infratentorial hyperintensities, and posterior circulation territory infarctlike lesions.
Cognitive function was also measured.

Main Results:

Women with migraine exhibited a higher incidence of deep white matter hyperintensities compared to controls (77% vs. 60%).
No significant association was found between migraine and the progression of infratentorial hyperintensities or posterior circulation infarctlike lesions in women.
Migraine was not associated with any MRI-measured brain lesion progression in men, nor was migraine frequency linked to lesion progression or cognitive decline.

Conclusions:

Women with migraine have an increased risk of developing deep white matter hyperintensities over time.
Migraine in men is not associated with the progression of MRI-detected brain lesions.
Further research is needed to understand the long-term neurological implications of migraine.