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Epidemiology of viral hepatitis in Saudi Arabia: are we off the hook?
Ayman A Abdo1, Faisal M Sanai, Faleh Z Al-Faleh
1Department of Medicine, Gastroenterology Unit, King Khalid University Hospital, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Insights
Viral hepatitis, including hepatitis B (HBV) and hepatitis C (HCV), remains a global health concern. This review documents the epidemiological timeline of viral hepatitis in Saudi Arabia, highlighting disease trends and healthcare impacts.
Area of Science:
- Epidemiology
- Public Health
- Virology
Background:
- Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections affect millions globally, representing a significant epidemic.
- Despite declining prevalence in Saudi Arabia, HBV and HCV cause substantial morbidity, mortality, and healthcare burdens.
- Hepatitis A virus (HAV) seroprevalence has notably decreased in Saudi Arabia over the last two decades.
Purpose of the Study:
- To document the epidemiological timeline of viral hepatitis in Saudi Arabia.
- To summarize published literature on viral hepatitis epidemiology within the country.
- To identify gaps in understanding the clinical expression of viral hepatitis.
Main Methods:
- Literature review of published studies on viral hepatitis epidemiology in Saudi Arabia.
- Analysis of epidemiological data and trends over time.
- Synthesis of information regarding disease prevalence, morbidity, and mortality.
Main Results:
- Significant decline in HBV and HCV prevalence in Saudi Arabia noted.
- Substantial ongoing burden of HBV and HCV infection on healthcare systems.
- Considerable reduction in HAV seroprevalence over the past 20 years.
Conclusions:
- Viral hepatitis epidemiology in Saudi Arabia shows evolving patterns.
- Continued monitoring and research are essential to address remaining challenges and clinical expression details.
- Progress in understanding viral hepatitis trends aids public health strategies.
Abstract:
Some 400 million people worldwide are currently infected with the hepatitis B virus (HBV), and the infection is common in the Middle East. Another 170 million people around the globe presently live with chronic hepatitis C virus (HCV) infection. Both HBV and HCV represent a worldwide epidemic. Despite significant decline in the prevalence of HBV and HCV infection in Saudi Arabia, these viral diseases cause significant morbidity and mortality, and impose a great burden on the country's healthcare system. On the other hand, Saudi epidemiology studies have shown that the hepatitis A virus seroprevalence in the country has reduced considerably over the past two decades. The progress in mapping the epidemiological pattern of viral hepatitis in Saudi Arabia has not only aided our understanding of the disease, but has also exposed the small but relevant gaps in our identification of the intricate details concerning the disease's clinical expression. In this review, we aim to document the timeline of viral hepatitis epidemiology in Saudi Arabia, while summarizing the relevant published literature on the subject.
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