Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Signs of Puberty01:27

Signs of Puberty

Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterizing Onset Limit and Surgical Outcome Factors in Type II Focal Cortical Dysplasia-Related Epilepsy.

Neurology. Clinical practice·2026
Same author

Free-breathing Dynamic MRI Analysis of Three-dimensional Diaphragm Curvatures in Pediatric Patients with Thoracic Insufficiency Syndrome.

Radiology. Cardiothoracic imaging·2026
Same author

Imaging of complex lymphatic anomalies in children.

Pediatric radiology·2026
Same author

Educational Case: Meningioma.

Academic pathology·2026
Same author

Lymphatic Imaging Techniques: Evaluation of the Central Lymphatic System.

Seminars in roentgenology·2026
Same author

Pediatric Pulmonary Vein Stenosis and Treatment.

Seminars in roentgenology·2026

Related Experiment Video

Updated: May 16, 2026

Chromosome Preparation From Cultured Cells
07:42

Chromosome Preparation From Cultured Cells

Published on: January 28, 2014

From the radiologic pathology archives: precocious puberty: radiologic-pathologic correlation.

Ellen M Chung1, David M Biko, Jason W Schroeder

  • 1Department of Radiology and Radiological Sciences, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814, USA. ellen.hung@usuhs.edu

Radiographics : a Review Publication of the Radiological Society of North America, Inc
|November 15, 2012
PubMed
Summary

Precocious puberty diagnosis relies on imaging to identify causes like central nervous system lesions or adrenal/gonadal tumors. Imaging helps differentiate between hypothalamic-pituitary axis activation and independent sex steroid secretion.

Related Experiment Videos

Last Updated: May 16, 2026

Chromosome Preparation From Cultured Cells
07:42

Chromosome Preparation From Cultured Cells

Published on: January 28, 2014

Area of Science:

  • Pediatric Endocrinology
  • Diagnostic Imaging
  • Endocrinology

Background:

  • Precocious puberty presents diagnostic challenges, with imaging being crucial for identifying underlying causes.
  • Causes include inappropriate hypothalamic-pituitary axis activation or gonadotropin-independent sex steroid secretion from adrenal glands or gonads.
  • Various lesions, including central nervous system (CNS) abnormalities, adrenal lesions, and gonadal tumors, can manifest as precocious puberty.

Purpose of the Study:

  • To highlight the critical role of diagnostic imaging in evaluating precocious puberty.
  • To outline the diverse etiologies of precocious puberty, emphasizing imaging modalities for each.
  • To differentiate between central and peripheral causes of precocious puberty based on imaging findings.

Main Methods:

  • Brain magnetic resonance imaging (MRI) is essential for evaluating CNS lesions causing precocious puberty, particularly in boys.
  • Ultrasonography is the primary imaging modality for assessing the sex organs (ovaries and testes) and can also evaluate adrenal abnormalities.
  • Review of neoplastic and non-neoplastic conditions affecting the hypothalamic-pituitary axis, adrenal glands, and gonads.

Main Results:

  • CNS lesions, including neoplastic (astrocytoma, germinoma) and nonneoplastic (hamartoma, hydrocephalus) conditions, are common causes, especially in boys.
  • Adrenal causes include neoplasms (adrenal cortical neoplasms, ACNs) and hyperplasia, with distinct presentations based on age and genetic factors.
  • Ovarian causes in females include autonomously functioning cysts and granulosa cell tumors; testicular tumors (Leydig, Sertoli cells) cause male precocious puberty.

Conclusions:

  • Imaging plays a pivotal role in the diagnostic workup of precocious puberty, guiding etiological identification.
  • Tailored imaging strategies, including MRI and ultrasonography, are crucial for evaluating potential central and peripheral causes.
  • Understanding the diverse origins of precocious puberty is essential for appropriate diagnostic and therapeutic management.