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Synthesis and post-polymerisation modifications of aliphatic poly(carbonate)s prepared by ring-opening polymerisation
Sarah Tempelaar1, Laetitia Mespouille, Olivier Coulembier
1Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.
Chemical Society Reviews
|November 16, 2012
Summary
Aliphatic poly(carbonate)s are versatile for biomedical uses due to their safety and degradability. This review covers their synthesis, polymerization, and modification for advanced functional materials.
Area of Science:
- Polymer Chemistry
- Biomaterials Science
- Organic Synthesis
Background:
- Aliphatic poly(carbonate)s offer low toxicity, biocompatibility, and biodegradability, making them ideal for biomedical applications.
- The synthetic flexibility of cyclic carbonates enables the creation of functional, degradable polymers via ring-opening polymerization.
Purpose of the Study:
- To review recent advancements in the synthesis and ring-opening polymerization of functional cyclic carbonates.
- To discuss post-polymerization modification techniques and material applications.
Main Methods:
- Literature review of studies published in the last decade.
- Analysis of synthetic strategies for functional cyclic carbonates.
- Examination of ring-opening polymerization techniques.
- Overview of post-polymerization modification methods.
Main Results:
- Detailed discussion on the synthesis of diverse functional cyclic carbonates.
- Elucidation of various ring-opening polymerization methods yielding poly(carbonate)s.
- Exploration of post-polymerization modification for tailored material properties.
- Compilation of applications for these advanced poly(carbonate) materials.
Conclusions:
- Functional cyclic carbonates are key building blocks for advanced degradable polymers.
- Ring-opening polymerization and post-modification offer precise control over material characteristics.
- These poly(carbonate)s show significant promise for diverse biomedical applications.
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