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Updated: May 16, 2026
07:11
Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
Mid-term differences in right ventricular function in patients with congenital diaphragmatic hernia compared with
Matthew J Egan1, Nazia Husain, Jack R Stines
1The Heart Center, Nationwide Children's Hospital, Columbus, OH, USA.
World Journal of Pediatrics : WJP
|November 16, 2012
Summary
Congenital diaphragmatic hernia (CDH) repair patients show lasting right ventricular (RV) function differences. Echocardiography reveals impaired RV diastolic and systolic waves and reduced strain in repaired CDH patients years later.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Cardiac Imaging
Background:
- Congenital diaphragmatic hernia (CDH) can lead to abnormal lung development and negatively impact right ventricular (RV) function.
- Persistent RV dysfunction may affect long-term cardiac health in CDH survivors.
Purpose of the Study:
- To investigate persistent echocardiographic differences in RV function in patients who underwent CDH repair compared to control subjects.
- To assess long-term cardiac outcomes in pediatric CDH survivors.
Main Methods:
- Recruitment of patients with a history of CDH repair and age-matched controls.
- Evaluation of RV function using strain analysis and tissue Doppler imaging (TDI).
- Statistical analysis using Wilcoxon's rank-sum test.
Main Results:
- No significant age difference between CDH (n=7) and control (n=16) groups.
- CDH patients exhibited significantly lower RV early diastolic wave (12.8±1.5 cm/s vs. 16.1±3.1 cm/s) and RV systolic wave (10.2±0.8 cm/s vs. 13.4±1.3 cm/s) via TDI.
- Lower interventricular apical septal strain (-20.1±4.6% vs. -25.4±4.1%) and a trend towards lower global RV strain (-27.8±3.0% vs. -31.1±3.1%) in CDH patients.
Conclusions:
- Patients repaired for CDH demonstrate persistent alterations in RV function years post-surgery.
- Further follow-up is crucial to understand the long-term impact of these RV functional differences on adult CDH survivors.
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