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Published on: November 9, 2016
Interventions for drooling in children with cerebral palsy
Margaret Walshe1, Martine Smith, Lindsay Pennington
1Clinical Speech and Language Studies,Trinity College Dublin, Dublin 2, Ireland. walshema@tcd.ie
This review found insufficient evidence to conclude the effectiveness of interventions for drooling in children with cerebral palsy (CP). Further research is needed to guide clinical practice for managing drooling in CP patients.
Area of Science:
- Pediatric Neurology
- Rehabilitation Medicine
Background:
- Drooling is a prevalent and distressing issue for children with cerebral palsy (CP).
- Consequences include social rejection, hygiene issues, infections, and communication difficulties.
- Current interventions for drooling in CP lack consensus on effectiveness.
Purpose of the Study:
- Evaluate the effectiveness and safety of interventions for reducing drooling in children with CP.
- Provide evidence to inform clinical practice and guide future research.
- Assess interventions including pharmacological and botulinum toxin-A treatments.
Main Methods:
- Systematic search of multiple databases (inception to December 2010) and clinical trial registries.
- Inclusion of only randomized controlled trials (RCTs) and controlled clinical trials (CCTs).
- Independent data extraction and resolution of discrepancies.
Main Results:
- Six studies were included: four on botulinum toxin-A (BoNT-A) and two on pharmacological agents (benztropine, glycopyrrolate).
- No trials on surgery, therapies, behavioral interventions, or acupuncture were found.
- All included studies showed short-term statistically significant changes but had methodological flaws; meta-analysis was not possible due to heterogeneity.
Conclusions:
- Insufficient evidence exists to determine the effectiveness and safety of BoNT-A or pharmaceutical interventions for drooling in children with CP.
- Current evidence cannot inform clinical practice for managing drooling in this population.
- Further high-quality research is required to establish effective interventions.
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