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Harmonic Nanoparticles for Regenerative Research
Published on: May 1, 2014
Nonlinear nanomedecine: harmonic nanoparticles toward targeted diagnosis and therapy
1GAP-Biophotonics, University of Geneva, 22 chemin de Pinchat, CH-1211 Geneva 4, Switzerland. luigi.bonacina@unige.ch
Molecular Pharmaceutics
|November 17, 2012
Abstract:
Harmonic nanoparticles were first introduced in 2006 as biomarkers for nonlinear imaging. This review provides a general explanation of the physical mechanism at the basis of this novel approach, highlighting its benefits and the complementarity to fluorescent/luminescent labels. A series of application examples from the very recent literature are reported, ranging from in vitro cell monitoring to the first proofs of in vivo imaging and rare event detection in physiological fluids.
